ChIN简介页:Distributed Structure-Searchable Toxicity (DSSTox) Public Database Network
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Distributed Structure-Searchable Toxicity (DSSTox) Public Database Network

【URL】 http://www.epa.gov/nheerl/dsstox/

【简介】
     The Distributed Structure-Searchable Toxicity (DSSTox) Database Network provides a community forum for publishing standard format, structure-annotated chemical toxicity data files for open public access.

Available databases

CPDBRM, CPDBHA, CPDBDO, CPDBPR: Carcinogenic Potency Database Summary Tables for Rat&Mouse, Hamster, Dog, and Non-human Primates
Tumor target site incidence and TD50 potencies for 1354 chemical substances tested in rats and mouse, 80 chemical substances tested in hamsters, 5 chemicals tested in dogs, and 27 chemical substances tested in non-human primates; data reviewed and compiled from literature and NTP studies.
(SDF last updated 15Oct03)

DBPCAN: Water Disinfection By-Products Database with Carcinogenicity Estimates
Carcinogenicity estimates (high, moderate, low concern) by EPA experts using a mechanism-based analog SAR approach on a set of 209 water disinfection by-products, mostly small halogenated organics.
(SDF last updated 12Sep03)

EPAFHM: EPA Fathead Minnow Aquatic Toxicity Database
Acute toxicities of 617 chemicals tested in common assay, with mode-of-action assessments.and confirmatory measures.
(SDF last updated 15Oct03)

NCTRER: FDA’s National Center for Toxicological Research - Estrogen Receptor Binding Database
Estrogen receptor relative binding affinities tested in a common in vitro assay for 232 chemicals, listed with chemical class-based structure activity features.
(SDF last updated 7Nov03)


Summary by 李晓霞 on 2004-03-30

Last updated by 李晓霞 on 2004-09-09

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