Tripos, Inc. (计算机辅助药物设计)
Tripos is a leading provider of discovery research software and services to pharmaceutical, biotechnology and other life sciences companies worldwide.
The company is dedicated to simplifying and accelerating the discovery of new products in the pharmaceutical and related industries. Tripos offers "chemically intelligent" discovery software tools to manage, analyze and share biological and chemical information; systems integration services; diverse chemical libraries; and contract research for the identification and synthesis of new chemical compounds that are active in biological systems.
Tripos provides a variety of high quality software through a common SYBYL? interface that simplifies and accelerates the discovery of drugs and new chemical entities in the agrochemical, pharmaceutical, and biotechnology industries.
Molecular Modeling and Visualization: Build, view, and compare structures...Calculate and explore molecular properties...Create and display molecular surfaces
SYBYL/base | Advanced Computation | MM2 ('91) | MM3 (2K) | AMPAC | MOLCAD | Confort
Chemical Information Systems: Create and explore chemical and biological databases...Decision support software...Compound databases for lead identification
UNITY | CONCORD | Molconn-Z | StereoPlex | ChemEnlighten | Commercial Databases
Pharmacophore Perception: Automatically align molecules...Identify correspondences between ligands...Determine 3D conformation of ligands bound to a target
DISCO | FlexS | GASP | Receptor
Combinatorial Chemistry & Molecular Diversity: Design and create virtual compound libraries...Compare the diversity of libraries...Select diverse and representative library subsets
Legion | CombiLibMaker | Selector | DiverseSolutions
Structure-Activity Relationships: Calculate molecular properties...Relate molecule structure to property...Build statistical and graphical models that predict activity
QSAR with CoMFA | Advanced CoMFA | Common Substructure | HQSAR | ClogP/CMR | HDISQ | Topkat
Structural Biology and Bioinformatics: Predict and build 3D protein structures...Analyze and evaluate macromolecule structures...Identify protein function from sequence
Composer | ProTable | GeneFold | Matchmaker
Macromolecule-Based Drug Design: Build, view and edit macromolecule structures...Locate binding sites... Screen virtual compound libraries...De novo ligand design
Biopolymer | SiteID | FlexX | CScore | LeapFrog
NMR Analysis and Structure Generation: Process and visualize multi-dimensional NMR data...Automatically assign spin networks...Extract distance restraints... Calculate structures
TRIAD | CAPRI | MARDIGRAS+ | DYANA
Desktop Modeling and Data Analysis: Display and explore molecules at the desktop...Create QSAR models...Analyze protein structure...Predict polymer properties
Alchemy 2000 | SciLogP | SciPolymer | SciProtein | SciQSAR
LeadQuest Compound Libraries:
LeadQuest is a growing compound library of greater than 50,000 compounds that meet our diversity and purity criteria. LeadQuest's compounds are based on a general understanding of biological relevance and are suitable for initial screening of any biological test system.
Aeon Technology Inc
Summary by 李晓霞 on 2000-09-11
Last updated by 李晓霞 on 2003-03-12