By Congressional mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) produces "toxicological profiles" for hazardous substances found at National Priorities List (NPL) sites. These hazardous substances are ranked based on frequency of occurrence at NPL sites, toxicity, and potential for human exposure. Toxicological profiles are developed from a priority list of 275 substances. ATSDR also prepares toxicological profiles for the Department of Defense (DOD) and the Department of Energy (DOE) on substances related to federal sites.
So far, 261 toxicological profiles have been published or are under development as "finals" or "drafts for public comment"; 244 profiles were published as finals; 103 profiles have been updated. Currently, 11 profiles are being revised based on public comments received and 1 profile is being developed as public comment draft. These profiles cover more than 250 substances.
Toxicological profiles are developed in two stages:
(1) DRAFTS: The toxicological profiles are first produced as drafts. ATSDR announces in the Federal Register the release of these draft profiles for a 90-day public comment period. Request draft toxicological profiles from ATSDR's Division of Toxicology (DT).
(2) FINALS: After the 90-day comment period, ATSDR considers incorporating all comments into the documents. ATSDR finalizes the profiles and the National Technical Information Service (NTIS) distributes them.
NTIS distributes finalized toxicological profiles for a fee. For more information, contact:
National Technical Information Service
5285 Port Royal Road
Springfield, Virginia 22161
800-553-6847 or 703-605-6000
NTIS Web Site: www.ntis.gov
美国毒物与疾病登记署Agency for Toxic Substances and Disease Registry (ATSDR)
Analysis Paper: Impact of Lead-Contaminated Soil on Public Health (分析报告: 铅污染土壤对人类健康的影响)
ATSDR - ToxFAQs: Hazardous Substance Fact Sheets (危险品事实数据库)
Summary by 李晓霞 on 2002-11-08
Last updated by 何莉 on 2003-12-03